Uprima Information for Male Impotence Information
The following
Uprima frequently asked question section is for informational purposes
only. The information has been compiled from a variety of resources
in order to give the reader an overview of Uprima treats impotence.
What
is Uprima?
What
is the median time from dissolving Uprima under the tongue and the onset
of an erection?
What
are the most common side effects associated with the use of Uprima?
Will
Uprima allow me to have an erection for hours?
What
types of results did Uprima produce during clinical trials?
What
are the precautions/warnings concerning Uprima?
May
I consume alcohol while taking Uprima?
Does
Uprima affect my ability to drive or operate heavy equipment?
What
if Uprima does not produce the desired effects that I anticipated?
Does
the use of Uprima offer any protection against sexually transmitted
diseases?
Should
I use Uprima if I have not had sexual intercourse in a long time?
Can
I get Uprima over the counter?
Is
Uprima less effective in treating impotence that is secondary to certain
underlying medical conditions?
What
happens if there is no sexual stimulation following the ingestion of
Uprima?
Can
Uprima be combined with other treatments for impotence?
Are
there any populations were Uprima has not been clinically tested?
Is
there a potential for Uprima to be used in the treatment of impotence
in women?
What is Uprima?
Uprima (apomorphine) is one of the most recent impotence medications
on the market designed to help men achieve and maintain a sufficient
erection for intercourse.
What
is the median time from dissolving Uprima under the tongue and the onset
of an erection?
Clinical studies have shown:
34% of the erections
occurred within 10 minutes of dissolving the Uprima tablet under the
tongue.
66% of the erections occurred within 20 minutes of dissolving the Uprima
tablet under the tongue.
Will
Uprima allow me to have an erection for hours?
Once an individual ejaculates his erection will return to the normal
flaccid state. Uprima, however, can shorten the resolution phase or
the time it takes to achieve another erection.
What
types of results did Uprima produce during clinical trials?
Rome -- Men with erectile dysfunction (ED) who responded to UPRIMA(R)
(apomorphine hydrochloride SL) showed consistently high rates of success
over 18 months, according to data presented at the 4th Congress of the
European Society for Sexual and Impotence Research (ESSIR). Across the
entire study period, an average of 92 percent of attempts resulted in
an erection firm enough for intercourse among patients taking UPRIMA
2 mg(1). Efficacy was measured as the percentage of attempts resulting
in an erection firm enough for intercourse with UPRIMA, according to
patient and partner diary assessments. Both patient and partner evaluations
confirmed the success rate.
The findings provide
important evidence of the long-term efficacy of UPRIMA, the first centrally
acting oral therapy to be approved for the first- line treatment of
erectile dysfunction.
What
are the precautions/warnings concerning Uprima?
Individuals who have the following medical conditions should not take
Uprima:
- Cardiovascular
complications i.e. heart attack, congestive heart failure, unstable
angina (chest pain), uncontrolled hypertension or hypotension, history
of postural hypotension, stroke,
- Compromised renal
or hepatic function
- Abnormally formed
penis i.e. angulation, cavernosal fibrosis, Pyronie's disease
- Uprima should
not be used in men where sexual activity is inadvisable
Medications:
Patients taking
certain medications to treat medical conditions i.e. nitrate medications,
certain hypertensive medications, centrally acting dopamine agonist
or antagonists.
Note: Nitrates are
found in many prescription medications used to treat angina (chest pain
secondary to heart disease). Nitrates are also found in recreational
drugs.
- Nitroglycerin
( skin patches or pastes, sprays, ointments and tablets that are used
orally)
- Isosorbide mononitrate
and isosorbide dinitrate (tablets that are swallowed, chewed or dissolved
in the mouth)
- Nitrates are
found in recreational drugs i.e. amyl nitrate or nitrate ("poppers").
Individuals who are not sure if any of their medications contain nitrates
should consult with their healthcare professional prior to using Uprima.
Men who are taking
medicines that contain nitrates (Nitroglycerin) of any kind must never
use Uprima. Patients should not take Uprima even if you only take nitroglycerin
medication occasionally.
May
I consume alcohol while taking Uprima?
Consuming alcohol while taking Uprima is not recommended. The combination
may increase the possibility of hypotension (low blood pressure). In
addition, alcohol may reduce sexual performance.
Does
Uprima affect my ability to drive or operate heavy equipment?
Driving or using heavy equipment is not recommended while using Uprima.
Some individuals experience some dizziness or even light-headedness
while taking the medication. The side effects usually reside within
a few hours from your last dose.
What
if Uprima does not produce the desired effects that I anticipated?
If Uprima does not produce the desired effects do not despair. Uprima
is just one in many treatment options for erectile dysfunction (please
see the erectile dysfunction information section).
Does
the use of Uprima offer any protection against sexually transmitted
diseases?
No, the use of Uprima offers no protection against sexually transmitted
diseases, including HIV. Patients should continue to use protective
measures necessary to guard against these diseases.
Should
I use Uprima if I have not had sexual intercourse in a long time?
Sexual activity can cause a strain on the cardiovascular system. If
you have not had any physical activity or if you have any pre-existing
medical conditions you should consult with your local physician prior
to using the medication.
Can
I get Uprima over the counter?
No, Uprima should only be taken by prescription from a licensed physician.
Regulations do not permit Uprima to be taken without prescription. Secondary
to the advent of the internet individuals may now order Uprima online
simply by completing an online medical questionnaire. Subsequently,
a licensed physician will review your medical history and patient profile.
If approved for a Uprima prescription, your order shipped discreetly and promptly to your home or office (order
Uprima online now).
Is
Uprima less effective in treating ED that is secondary to certain underlying
medical conditions?
This question is somewhat difficult to answer right now. More data is
expected in the near future. Some initial data suggests that men, who
have undergone radical prostatectomy (surgical removal of their prostate),
using nerve-sparing procedures, are not achieving the same positive
results with Uprima.
What
happens if there is no sexual stimulation following the ingestion of
Uprima?
Uprima is naturally eliminated from your body in a few hours.
Can
Uprima be combined with other treatments for impotence?
The use of such combined treatments is not recommended, since no studies
have been done to access Uprima's safety and effectiveness.
Are
there any populations were Uprima has not been clinically tested?
Yes, there are several medical conditions were the effectiveness of
Uprima havecnot been clinically tested i.e. patients with spinal cord
injuries, multiple sclerosis, status post pelvic surgery including radical
prostatectomy.
Is
there a potential for Uprima to be used in the treatment of impotence
in women?
There are currently several medical research centers that are studying
whether Uprima is a viable oral therapy for woman. Unfortunately, secondary
to their anatomy, researchers know less concerning female sexual dysfunction
than with the male sexual dysfunction. Historically, research has focused
on male sexual dysfunction. Until we have a better understanding of
the physiological processes causing sexual dysfunction in women are
ability to treat the condition is limited.